Childhood Cancer 2012 brought together an outstanding line-up of speakers from a range of different research disciplines to speak on aspects of childhood cancer and early exposures.
The panel of invited speakers were joined by the authors of 25 submitted abstracts, representing a cross-section of over 100 excellent abstracts submitted for poster presentation.
We are pleased to be able to make available videos of some of the presentations and copies of some of the speakers' slides. You can access these by clicking on the links next to speakers' names below.
Tuesday, 24th April 2012 |
| 08:00 |
Open for registration |
| 09:45 |
SESSION 1 - Setting the scene
Chair:
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Welcome on behalf of CHILDREN with CANCER UK
Professor Denis Henshaw | View welcome video
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Opening address
Professor Sir Alan Craft | View slides | View opening address
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Keynote address
Professor David Barker | View slides | View presentation
The intrauterine origins of cancer
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Mr Charles Stiller | View slides | View presentation
National and international childhood cancer incidence and time trends
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| 11:20 |
Coffee |
| 11:45 |
SESSION 2 - The prognosis for children diagnosed with cancer in the 21st century
Chair:
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Dr Anupama Rao
Acute lymphoblastic leukaemia
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Dr Darren Hargrave
Childhood CNS tumours
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Professor Kathy Pritchard-Jones
Childhood non-CNS solid tumours
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Discussion | View discussion
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| 13:15 |
Lunch and posters |
| 14:30 |
SESSION 3 - Genetic and epigenetic aspects of childhood cancer risk
Chair:
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Professor Nazneen Rahman | View slides | View presentation
Genetic susceptibility to childhood cancer
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Professor Joseph Wiemels | View slides | Presentation pending publication of data
Epigenetic changes and childhood cancer
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Proffered paper | View slides | View presentation
Dr Elizabeth Perdeaux - GWAS identifies six loci, implicating the planar cell polarity pathway and the MYCN-DDX1 2p24.3 amplicon region in Wilms tumor susceptibility
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Proffered paper
Dr Amy Sherborne - Developmental timing of mutations in childhood leukaemia: insights from genome sequencing in twin pairs with ALL
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Proffered paper | View slides | View presentation
Sanne van Otterdijk - Does childhood leukaemia develop in cells which are pre-primed by the presence of aberrant patterns of DNA methylation?
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Proffered paper | View slides | View presentation
Dr Ariadna Mendoza-Naranjo - ErbB4 is a novel driver of metastasis and chemoresistance in Ewing sarcoma
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Discussion | View discussion
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| 16:30 |
Tea and posters |
| 17:00 |
SESSION 4 - Birth characteristics
Chair:
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Proffered paper | View slides | View presentation
Dr Lisbeth Samsø Schmidt - Birth characteristics and the subsequent risk of childhood CNS tumours and Incidence of childhood CNS tumours in the Nordic countries
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Proffered paper | View presentation
Dr Kate O'Neill - Infant birth weight as a risk factor for childhood cancer
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Proffered paper
Professor Peggy Reynolds - Birth defects as clues to the aetiology of cancer in children
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Proffered paper | View slides | View presentation
Dr Jérémie Rudant - Use of fertility treatments and childhood acute leukaemia: the ESCALE study
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Discussion | View discussion
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| 18:00 |
Wine reception and poster viewing |
Wednesday, 25th April 2012 |
| 08:30 |
SESSION 5 - Air pollution and smoking
Chair:
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Introduction to air pollution and smoking
Professor Denis Henshaw | View introduction
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Dr Mathuros Ruchirawat
DNA damage and repair in children exposed to benzene and carcinogenic compounds in ambient air
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Proffered paper
Professor Peggy Reynolds - Hazardous air pollutants and risk of childhood brain tumours in California
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Proffered paper
Dr Julia Heck - Traffic-related air pollution and childhood cancers in Los Angeles county
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Proffered paper | View slides | Presentation not yet available
Dr Catherine Metayer - Effects of tobacco smoking on the risks of childhood acute lymphocytic and myeloid leukaemias, by phenotypic and cytogenetic subtype
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Proffered paper
Professor Elizabeth Milne - Parental pre-natal smoking and risk of childhood acute lymphoblastic leukaemia
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Proffered paper | View slides | View presentation
Jessica Trimis - Parental smoking and risk of childhood brain tumours by functional polymorphisms in polycyclic aromatic hydrocarbon metabolism genes
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Discussion | View discussion
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| 10:30 |
Coffee and posters |
| 11:00 |
SESSION 6 - Aspartame, pesticides and other chemical exposures
Chair:
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Dr Morando Soffritti | View slides | View presentation
Aspartame and sucralose: the experimental evidence of cancer risk
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Professor Claire Infante-Rivard | View slides | View presentation
Exposure to pesticides and childhood cancer risk
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Proffered paper | View slides | View presentation
Dr Gisele Moledo de Vasconcelos - PON1 polymorphisms and the risk of Wilms tumour
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Proffered paper
Dr Sergio Koifman - Pregnancy, maternal exposure to hair dyes or hair straightening cosmetics and early age leukaemia in Brazil
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Proffered paper | View slides | View presentation
Dr Lucia Miligi - SETIL study: risk of childhood cancers in relation to parental occupational exposure
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Discussion View discussion
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| 12:45 |
Lunch and poster viewing |
| 13:45 |
SESSION 7 - Non-ionising radiation
Chair:
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Professor Richard Stevens | View slides | View presentation
Electric light, circadian disruption and cancer risk
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Professor Elisabeth Cardis | View slides | View presentation
Rationale for the IARC 2b classification for ELF and RF EMF
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Professor Denis Henshaw | View slides | View presentation
How might power frequency magnetic fields cause increased risk of childhood leukaemia?
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Discussion | View discussion
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| 15:30 |
Tea and posters |
| 16:00 |
SESSION 8 - Brain tumours, mobile phones and childhood cancer
Chair:
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Professor Geoff Pilkington | View slides | View presentation
Brain tumours: complexity in type, biology and origin
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Professor Dariusz Leszczynski | View slides | View presentation
Possible mechanism of cell phone radiation-induced brain cancer
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Proffered paper
Tina Veje Andersen - Mobile phone use, patterns of infectious disease, social contacts in early life and brain tumours in children and adults: an international case-control study (CEFALO)
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Discussion | View discussion
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| 17:30 |
Day two close |
| 19:30 |
CONFERENCE DINNER, Royal College of Physicians |
Thursday, 26th April 2012 |
| 08:30 |
SESSION 9 - Ionising radiation
Chair:
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Professor Richard Wakeford | View slides | View presentation
Ionising radiation and childhood cancer overview
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Professor Yuri Dubrova | View slides | View presentation
Radiation genetics, epigenetics and effects on clock genes
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Professor Kevin Prise
Bystander signalling - a future perspective
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Proffered paper | View slides | View presentation
Dr Richard McNally - Increasing incidence and geographical analysis of thyroid cancer in Great Britain, 1976 to 2005
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Discussion | View discussion
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| 10:15 |
Coffee and posters |
| 10:45 |
SESSION 10 - Infection and immunity
Chair:
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Dr Kevin Urayama | View slides | Presentation not available
Early life exposures to infectious agents and childhood cancer risk
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Proffered paper | Slides and presentation not yet available
Srividya Swaminathan - Infectious origins of childhood leukaemia
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Proffered paper | View slides | View presentation
Dr Giorgia Randi - A childhood leukaemia cluster in Milan: possible role of pandemic AH1N1 swine flu virus
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Discussion | View discussion
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| 12:00 |
Lunch and posters |
| 13:00 |
SESSION 11 - Diet
Chair:
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Professor Eleni Petridou | View slides | View presentation
Maternal and child dietary habits and childhood leukaemia risk
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Proffered paper | View slides | View presentation
Professor Anand Chokkalingam - Folate and childhood leukaemia risk
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Proffered paper | View slides | View presentation
Alicia Amigou - Folic acid supplementation, MTHFR and MTRR polymorphisms and the risk of childhood leukaemia: the ESCALE study
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Discussion | View discussion
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| 14:00 |
Tea Break |
| 14:30 |
SESSION 12 - What positive steps can be taken to reduce the risk of childhood cancer?
Chair: Professor Richard Stevens
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Professor Annie Sasco | View slides | View presentation
Alliance of prevention and precaution for childhood cancer control
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Proffered paper | View slides | View presentation
Professor Pat Buffler - The Childhood Leukemia International Consortium (CLIC)
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Proffered paper | View slides | View presentation
Professor Terry Dwyer - The International Childhood Cancer Cohort Consortium (I4C)
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Dr Somdat Mahabir
Report on NIH efforts to tackle early-life exposures and cancer
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Panel discussion: "In terms of public health policy what positive steps can be taken to reduce the risk of childhood cancer?" - leading into a general discussion: "What are the key messages from the conference?"
View discussions: Panel discussion | General discussion
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| 16:30 |
CLOSING SESSION
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Poster prize presentation | View prize presentations
Closing talk | View closing session and talk
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| 17:00 |
Close of conference |
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